Molecular Epidemiology Approach Towards Pancreatic Cancer (PaC)
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Project Summary
Molecular pathological epidemiology (MPE) has contributed to the better understanding of several neoplastic diseases . By connecting putative etiological factors to specific molecular signatures across tumour phenotypes, the MPE approach can yield more accurate risk measures regarding PaC. Towards this broad goal, a case-control study will be conducted first on patients with different types of pancreas cancer and pancreatico-biliary diseases to identify associations among potential risk factors and PaC diagnosis and prognosis.
Project population
Patients within Barts Health NHS Trust
Project cohort
Patients with pancreatic cancers and pancreatico-biliary diseases attending at the hospitals or reported in the GP data since 2010.
Project criteria
Full GP dataset to include:
- General
- Diagnosis
- Symptoms
- Medical history
- Lifestyle
- Physical exam
- Family history
- Blood test
- Urine test
- Surgical procedures
- Medication-SNOMED